James and Jean Culver Vision Discovery Institute

Annual Scientific Meetings

The Culver Vision Discovery Institute gathers annually to present the progress and innovation within the member labs. This structured meeting features both intra and extramural lecturers. The keynote address is delivered by individuals whose scope of research has proven its impact at the national or international level.

The intramural lectures are selected to showcase work being done locally. Most of the labs have posters displayed for review in the poster sessions or between lectures. The meeting generally closes with a group discussion on future direction and strategic planning. This includes discussion on translational merit and impact and consideration for future speakers and formats.

4th Annual Vision Discovery Institute Retreat

Thursday, March 15th, 2012 - Friday, March 16th, 2012   (Agenda below)

Keith Green Lecturer: John Dowling, Ph.D.
University: Harvard University, Cambridge Campus
Rank: Harvard College Professor
Role: Section of Molecular & Cellular Biology
Role: Llura and Gordon Gund Professor of Neuroscience

Location: River Room, Saint Paul's Church
Inaugural Keith Green Lecture
The late Dr. Keith Green joined the then Medical College of Georgia as Director of Ophthalmology Research in 1974. In 1978 he was appointed as the third Regents' Professor (highest academic status in the University System of Georgia). Dr. Green instructed many across the academic spectrum throughout his tenure here and is specifically noted for having published 330 scientific articles and contributed to 30 research texts. In honor of his achievements a named lectureship has been established. Dr. John Dowling will provide the inaugural keynote address in this annual series.

Thursday evening a reception is being held in honor of Dr. John Dowling. This will be held at the same venue as the poster sessions and lectures. Please join us for this time of interaction

Lecture & Poster Session
In addition to the keynote and plenary lectures by our invited speakers will be a number of other talks. Six will be given by our junior and senior Ophthalmology residents. The ophthalmology residents are required to perform research while in residency. The first year residents will be preparing a poster with the second and third year residents giving a presentation. There will be speakers from the basic science staff to round out the topics. Please watch the schedule for updates!


The Posters Expected: 20
1. Juan Mo, M.S.
Effect of Chlorquine or Rapamycin Treatment on Autophagy and Apoptosis during Murine Cytomegalovirus (MCMV) Infection of the Retina or RPE Cells.
2. Priya Narayanan Namboothiri, Ph.d.
Role of NOX2 NADPH Oxidase in Ischemia-Induced Retinal Neuronal Cell Death
3. Zhiyong Yang, Ph.D.
A Statistical Model of Scene Categorization
4. Megan Randazzo, M.D.
Cognitive Rehabilitation of Neuro- Ophthalmological Deficits Using the Neuroscientific Principles of Ambiguity Reduction.
5. Scotty Gadlin, M.D.
Outcomes of Patients on Ophthalmic Tacrolimus.
6. Shivani Sethi, M.D.
Identification of TGF Beta Regulated Protein in Aqueous Humor
7. Islam Mohamed, M.S.
Obesity-induced Retinal Microvascular Degeneration: Suggested Role of Thioredoxin Interacting Protein (TXNIP)
8. Shanu Markand, M.S.
CBS Expression in Mouse Retina
9. Steven Walker, BS
Analysis of Gene Expression Changes Occurring During Cell Specific Loss and Regeneration in the Zebrafish Retina
10. David White, B.S.
Forward Genetic Screen for Rod Photoreceptor Regeneration-Deficient Mutants in Zebrafish
11. Amany Tawfik, M.D.
Retinal Vascular Alterations in Cystathionine-Beta-Synthase (CBS) Mutant Mice: A Model of Excess Homocysteinemia
12. Barbara Mysona, Ph.D.
Inflammatory Role of ProNGF/p75NTP in Retinal Müller Cells
13. Jutamas Suwanpradid, BS
Arginase 2 Deficiency limits Microglial/Macro-phage Activation and Prevents Hyperoxia-induced Vascular Injury in the Mouse Retina
14. Mohammad Naime*
Mechanism of Adenosine Signaling Dysfunction in Diabetic Retinopathy
15. Saif Ahmad*
Microglial Activation in Traumatic Optic Neuropathy (TON)
16. Junko Ariga*
Reciprocal Modulations of WNT Signaling Enhance Retinal Regeneration by Increasing Stem Cell Proliferation Rates and Promoting Cell-Specific Differentiation
17. Sylvia Megyerdi*
Caspase-14: A Novel Caspase with Potential Role in Diabetic Retinopathy
18. Amira Otham*
12/15-Lipoxygenase-derived Eicosanoids Induce Retinal Endothelial Cell Permeability: A Possible Role of NADPH Oxidase
19. Chaunte Stampley*
Regulation and Activity of Stat 3 in the Hypoxic Retina
20. Shawn Elms*
Arginase as a Therapeutic Target for Diabetic Therapy
*Incomplete degree information   
The Agenda
March 15th, 2012, Thursday
3:00 pm ~ Registration/Poster set-up
3:30 pm ~ Welcome/Introductory Remarks
3:45 pm ~ Andrea Prosser, M.D.
Chief Resident
Localization of Transgelin within Human Trabecular Meshwork
4:00 pm ~ Yonju Ha, Ph.D.
Postdoctoral Fellow
Diabetes Accelerates Ganglion Cell Loss in Mice Lacking Sigma Receptor 1
4:15 pm ~ Mark Trevino, M.D.
Second Year Resident
Genetics of Cell-Specific Retinal Regeneration
4:30 pm ~ Alan Saul, Ph.D.
Assistant Professor
Flexible Multifocal ERG
5:30 pm ~ Reception
March 16th, 2012, Friday
7:30 am ~ Registration and refreshments
8:00 am ~ Julian Nussbaum, M.D..
Welcome/Introductory Remarks
8:20 am ~ Peter Buckley, M.D.,
Introductory remarks
8:30 am ~ Sylvia Smith, Ph.D.,
VDI Update
8:45 am ~ Malcolm Luxenberg, M.D.
Reflections about Dr. Keith Green
9:00 am ~ Anastasios Costarides, M.D., Ph.D.
Introduction of 1st Annual Keith Green Lectureship
9:15 am ~ Sally Atherton, Ph.D.
Introduction of Keith Green Lectureship Keynote speaker, John Dowling, Ph.D.
9:30 am ~ John Dowling, Ph.D.
What can a Zebrafish see with only an OFF-Visual Pathway and Other Fish Stories
10:30 am ~ Break
10:45 am ~ Diego Espinosa, M.D.
Vision Loss in AMD
11:00 am ~ Brad Snead, M.D.
Prevalence of HFE Gene Mutation in ARMD
11:15 am ~ Jaya Pranava Gnana-Prakasam, Ph.D.
Loss of HFE Leads to Progression of Tumor Phenotype in Primary Retinal Pigment Epithelial Cells
11:30 am ~ Erin Walsh, M.D.
Morbidity and Mortality of Screening Examinations for Retinopathy of Prematurity
11:45 am ~ Abiodun Akinwuntan, Ph.D.
Vision and Driving
12:00 pm ~ Luncheon and Poster Session
1:30 pm ~ Modesto Rojas, M.D., Ph.D.
Mechanisms of Diabetic Retinopathy: The Role of NOX2 in Retinal vs. Bone Marrow-derived Cells
1:45 pm ~ Lauren Yancey, M.D.
The Role of Endocan in Diabetic Retinopathy
2:00 pm ~ Folami Lamoke
TXNIP: Alpha Arrestin, Inhibitor of the Anti-Oxidant Activity and Activator of the NLRP3 Inflammasome
2:15 pm ~ Ming Zhang, Ph.D.,
More Rapid NK Cell and Macrophage/Microglia Responses Induced in the Injected Eye by HSV-1 Lacking the Beclin-Binding (BBD)
2:30 pm ~ Nadeem Fatteh, M.D.
Role of Adenosine in Traumatic Optic Neuropathy
2:45 pm ~ Discussion of VDI Initiatives and Future Directions